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Viral Vectors Take On HIV Infection

The New England Journal of Medicine

HIV: Tied Down By Its Own Receptor

An engineered protein that binds to the envelope of HIV viruses protects monkeys against infection with a simian–human virus that causes AIDS. This gene-therapy approach might provide an alternative to elusive HIV vaccines.

Stopping HIV With An Artificial Protein

Now, a research team has shown that a lab-made molecule that mimics an antibody from our immune system may have more protective power than anything the body produces, keeping four monkeys free of HIV infection despite injection of large doses of the virus.

New Approach To Blocking H.I.V. Raises Hopes For An AIDS Vaccine

“It’s a twofer,” said Dr. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, which supported the work. “It’s very impressive, and the method is quite promising. But it’s still just in an animal model, so we’ll need to see evidence of whether it works in humans.”
The New York Times

Discovery Could Lead To New HIV, AIDS Therapy

Scientists have engineered a new molecule they say can block infection with HIV, the virus that causes AIDS.

HIV Vaccine That Transforms Cell DNA Brings Fresh Hope

Dr Anthony Fauci, of the US National Institutes of Health, said: "This innovative research holds promise for moving us toward two important goals: achieving long-term protection from HIV infection, and putting HIV into sustained remission in chronically infected people."
BBC News

Protection Without A Vaccine

By delivering synthetic genes into the muscles of the monkeys, the scientists are essentially re-engineering the animals to resist disease. Researchers are testing this novel approach not just against H.I.V., but also Ebola, malaria, influenza, and hepatitis.
The New York Times